The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25D-3), is a possible treatment for myeloid leukemia and other cancers. The drawback is that 1,25D-3 causes the blood levels of calcium to escalate. The authors demonstrated that a polyphenol of rosemary called carnosic acid enhances the effect of the 1,25D-3 so that a lower dose is effective against cancer without raising the blood calcium.
The current study was done using vitamin D and rosemary against a mouse model of myeloid leukemia. In this study the combination was found to be effective in treating myeloid leukemia in mice.
CONCLUSION: Clinical studies on humans remain to be done. The cancer treating potential of 1,25D-3 with the enhancing potential of carnosic acid from rosemary are emphasized by the author.
To read the author’s abstract of the article click on the link to the author’s title of the article above.
PMID: 16395705.
Summary #058.
