The authors studied the ouabain-like effect of sanguinarine (SG,) an alkaloid, and a derivative formed in the gastrointestinal tract, dihydrosanguinarine (DHSG,) on the sodium pump (Na(+)K(+)-ATPase.) The sodium pump maintains the intracellular pH by changing the flow of sodium and potassium ions across the cell wall. SG is found in the Papaveraceae, Fumariaceae and Rutaceae […]
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