Nitric Oxide in Health and Disease.

Posted on June 1, 2015 by Dr. Gary Pack

Nitric oxide (NO) is a chemical which functions in nearly every cellular activity of the body. NO in the walls of small blood vessels determines the tone of the blood vessels and controls blood flow. Abnormally low NO levels cause “endothelial dysfunction”*, with inability of blood vessel walls to relax. Low NO levels play a […]

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Anti-Hypertensive Nutraceuticals and Functional Foods.

Posted on May 15, 2015 by Dr. Gary Pack

High blood pressure (hypertension,) with blood pressure over 140/90, is a risk for stroke, kidney disease and heart disease. Alternative therapy is beneficial in hypertension, especially in early, mild hypertension that doesn’t need prescription treatment. Certain foods and herbs have chemical and relaxation functions similar to anti-hypertensive medications. A specific cause of essential hypertension cannot […]

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Glutamine as an Immunonutrient.

Posted on May 14, 2015 by Dr. Gary Pack

Immunonutrients, which improve immune function, have been shown to benefit patients at times of surgery or during critical illness. They improve immunity when given in large doses with resulting shorter hospital stays. Some examples are arginine, omega-3 fatty acids, glutamine, nucleotides (components of DNA and RNA), beta-carotene, and branched-chain amino acids. Glutamine amino acid is […]

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Arginine in Asthma.

Posted on August 16, 2012 by Dr. Gary Pack

L-arginine is metabolized by the arginase enzyme and by the nitric oxide synthase (NOS) enzyme. Abnormalities in the arginine and the arginase and nitric oxide synthase pathways can lead to airway hyperresponsiveness (AHR,) as seen in asthma. Exhaled levels of nitric oxide (NO) are elevated in asthma. Arginine therapy has been shown to be beneficial […]

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Conditions: Airway hyperresponsiveness, Asthma

Supplements: Arginine, Citrulline, Ornithine

Miscellaneous: Nitric oxide (NO), Nitric oxide synthetase, Peroxynitrite

Arginase: a Key Enzyme in Allergic Asthma.

Posted on August 16, 2010 by Dr. Gary Pack

Allergic asthma causes obstruction of bronchi and airway hyperresponiveness (AHR.) Eventually, there are inflammation and remodeling of the airways. The enzyme, arginase, may play a part in this. Reduced availability of arginine may be involved, resulting in problems with bronchoconstriction from reduced levels of nitric oxide (NO.) Arginine deficiency results in increased levels of peroxynitrite, […]

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Conditions: Asthma, Bronchoconstriction, Inflammation

Supplements: Arginine, Citrulline, Ornithine, Rhubarb (Rheum rhabarbarum)

Miscellaneous: Arginase, Nitric oxide (NO), Nitric oxide synthetase, Peroxynitrite, Polyamines, Prolines, Putrescine, Spermidine, Spermine, Urea

Nitric Oxide in Hypertension and Cardiovascular Disease.

Posted on March 1, 2007 by Dr. Gary Pack

Nitric oxide (NO) is a gas which is found throughout the human body, in plants and in insects, which is important for the following functions: Regulates blood vessel dilation. Prevents blood clot formation in blood vessels. Important in reproduction. Dilates bronchi in the lungs. Aids in bone formation. Works in memory function. Regulates insulin sensitivity. […]

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