Citrus and Cancer Prevention.

Posted on August 3, 2011 by Dr. Gary Pack

About one-third of all cancers are diet-related, so cancer prevention strategies usually focus on foods which reduce the development of malignancy. Beta-cryptoxanthin is a carotenoid related to vitamin A, and hesperidin is a flavonoid, both of which are known to inhibit cancer formation in various tissues. Of interest, fruits and vegetables contain only small amounts […]

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Conditions: Cancer, Colon cancer, Inflammation, Lung cancer, Tongue cancer

Supplements: Carotenoids, Hesperidin, Vitamin A

Foods: Citrus juice, Citrus pulp

Miscellaneous: Beta cryptoxanthin

Curcumin for the Prevention of Colorectal Cancer.

Posted on April 22, 2011 by Dr. Gary Pack

Aberrant crypt foci (ACF) are small lesions of the colorectal region which may be markers of colon carcinogenesis. ACF are found in the rectums of current and former tobacco smokers. Curcumin is a natural chemical derived from the turmeric plant. It has anti-inflammatory, antioxidant, and anticancer properties. Curcumin prevents the production of two chemicals called […]

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Conditions: Abberant cryptic foci, Carcinogenesis, Colon cancer, Diarrhea, Gastroesophageal reflux

Supplements: Curcumin, Turmeric (Curcuma longa)

Miscellaneous: COX-1, COX-2, COX-2 inhibitor, Eicosanoids, Prostaglandins

Radiation Carcinogenesis: Lessons From Chernobyl.

Posted on April 1, 2011 by Dr. Gary Pack

“Radiation is a carcinogen.” This has been known since the time of Marie Curie and confirmed by the experience of the Japanese from the atomic bombs at Hiroshima and Nagasaki. Marie Curie developed leukemia after doing research on radioactivity. Radiation causes DNA mutations in radiated cells which can be transmitted to later generations. It may […]

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Conditions: Breast cancer, Cancer, Carcinogenesis, Colon cancer, DNA damage, Leukemia, Mutation, Papillary thyroid cancer, Puberty, Radiation damage, Thyroid cancer

Foods: Milk

Miscellaneous: Atomic bomb, Cesium, Chernobyl, Curie (Madame Marie), Hiroshima, Iodine-131, Nagasaki, Radioactive strontium, Tellurium, Thyroid gland, Wind, Xenon

Paleolithic Nutrition: Twenty-Five Years Later.

Posted on December 14, 2010 by Dr. Gary Pack

The “evolutionary discordance hypothesis” was proposed 25 years ago as the connection between diet and “diseases of civilization.” The title of the article was “Paleolithic Nutrition: A Consideration of Its Nature and Current Implications,” by the same authors. The above theory says that diets have changed greatly since the days of our hunter-gatherer ancestors 10,000 […]

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Selenium for Cancer Prevention.

Posted on October 1, 2010 by Dr. Gary Pack

Selenium (Se) is a dietary trace element with anti-carcinogenic effects. Because of inadequate intake by many people, increasing the general Se intake would greatly reduce cancer risk. Se in the soil is taken up by plants grown in that soil. Plants grown in Se depleted soil will be low in Se. Cancer risk is lower […]

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Conditions: Brain cancer, Breast cancer, Bronchial cancer, Cancer, Colon cancer, Liver cancer, Lung cancer, Prostate cancer, Smokers, Stress

Supplements: Glutathione peroxidase, Selenium, Vitamin E

Foods: Cereal grains, Eggs, Meat, Milk, Seafood

Miscellaneous: Anticancer, Element, Japanese diet

Phytosome Complexes of Silymarin, Curcumin, Etc.

Posted on August 9, 2010 by Dr. Gary Pack

One class of very useful plant medicines is made up of polyphenols, mostly flavonoids. Polyphenols absorb poorly into water or lipids. The phytosome forms of polyphenols have improved oral absorption and are safe. They are used as anti-inflammatories, anti-neoplastics, for detoxification and for weight loss.Polyphenols bind strongly to phospholipids, even in intact plant tissue. Phosphatidylcholine […]

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Angiogenesis of Tumors and Omega-3 Fatty Acids.

Posted on May 13, 2010 by Dr. Gary Pack

Omega-3 fatty acids (FAs) are associated with a reduced risk of prostate, breast and colon cancers. There is evidence that omega-3 fatty acids are anti-angiogenic, anti-inflammatory, anti-apoptotic and anti-proliferative. This article is a review of the ways in which omega-3 fatty acids can reduce cancer risk. Angiogensis is the growth of new blood vessels. Angiogenesis […]

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Chemoprevention of Intestinal Cancer by Milk Thistle Silibin.

Posted on April 29, 2010 by Dr. Gary Pack

Chemoprevention, the chemical prevention of cancer, is an important part of colorectal cancer control. This article reviews a study of the ability of silibinin, a component of milk thistle (Silybum marianum,) to prevent colon cancer in mice. Mice prone to develop colon cancer, spontaneously, were fed silibinin. The animals were tested after 13 weeks of […]

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Conditions: Angiogenesis, Apoptosis, Bladder cancer, Cancer, Colon cancer, Colorectal cancer, Familial adenoma polyposis, Lung cancer, Polyps, Prostate cancer, Skin cancer, Small intestine cancer

Supplements: Milk thistle (Silybum marianum), Silibinin

Miscellaneous: Anti-angiogenesis, Nitric oxide synthetase

Apigenin, Chrysin, and Luteolin are Proteasome Inhibitors in Tumor Cells.

Posted on September 5, 2009 by Dr. Gary Pack

The proteasomes of cells regulate apoptosis (a natural form of cell death for abnormal cells.) Proteasome activity is increased in cancer cells. Proteasome inhibition arrests cell growth and induces apoptosis in abnormal cells. Proteasome inhibition is seen as a useful therapy against cancers such as multiple myeloma and non-Hodgkin’s lymphoma. Because of the toxicity of […]

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Conditions: Apoptosis, Cell death, Colon cancer, Leukemia, Liver cancer, Lung cancer, Multiple myeloma, Non-Hodgkin's lymphoma

Supplements: Bioflavonoids, Chrysin, EGCG (epigallocatechin gallate)

Foods: Coffee, Tea (Camellia sinensis), Wine

Miscellaneous: Anti-inflammatory, Anticancer, Antioxidant, Antiviral, Apigenin, Flavonoids, Luteolin, Proteasome, Proteasome inhibitors

Therapeutic Potential of Black Cumin Seeds.

Posted on March 7, 2009 by Dr. Gary Pack

Black cumin seed (Nigella sativa) has been used medicinally for centuries. Nigella is different from common cumin (Cuminum cyminum.) Black cumin is part of the Ranunculaceae family of plants. There is a reference in the Bible to black cumin. Research on an alcohol extract of Nigella sativa has shown antitumor and “lifespan expanding activity” in […]

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Conditions: Cancer, Colon cancer, Liver toxicity, Neurodegeneration, Prostate cancer, Schistosomiasis

Supplements: Black seed (Nigella sativa), EGCG (epigallocatechin gallate)

Miscellaneous: Antioxidant, Catechins, Thymoquinone

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