Uranium as an Endocrine Disrupter.

Posted on February 10, 2017 by Dr. Gary Pack

From the early 1950s until a market collapse in 1971, Uranium (U) mining was an active business in Southwestern U.S. Mining has been concentrated in the Four Corners region and the Navajo reservation. To this day, abandoned mines are heavy polluters and “10,000 gallons of U-contaminated water seeps into the Colorado (River) daily”. Of the […]

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Bisphenol A and Peripheral Arterial Disease.

Posted on October 15, 2016 by Dr. Gary Pack

Bisphenol A (BPA) is an additive to plastics, found in the urine of 93% of American adults. It is found in plastic and plastic-lined food and beverage containers where it leaches into our food and beverages. In animal studies, BPA levels in the body are associated with weight gain, insulin resistance, thyroid and other hormone […]

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Conditions: Arteriosclerosis (atherosclerosis), Bisphenol toxicity, Cardiovascular disease, Endocrine dysfunction, Insulin resistance, Peripheral artery disease, Thyroid disease, Weight gain

Miscellaneous: Bisphenol, Endocrine disruptors, Environment, Plastic

Aromatase in Testis Health.

Posted on April 20, 2015 by Dr. Gary Pack

Good health depends on balance between testosterone and estrogen in both males and females. Neither hormone is just “male” or “female”. The goal of this article was to study the effect of the aromatase enzyme in human testes, the effects of high and low hormone levels on the testes, as well as the location of […]

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Conditions: Aging, Bisphenol toxicity, Endocrine dysfunction, Hypospadias, Infertility, Klinefelter's syndrome, Testicular cancer, Testicular disease, Undescended testes

Supplements: Androstenedione, Dehydroepiandrosterone (DHEA), Kudzu (Pueraria lobata)

Miscellaneous: Aromatase enzyme, Endocrine disruptors, Estrogen, Testicles (testes), Testosterone

Bisphenol A and Inner Ear Development.

Posted on September 9, 2014 by Dr. Gary Pack

Bisphenol A (BPA) is an industrial chemical widely present in plastics. It is one of the worst contaminants in groundwater in the USA, with water levels at 0.14 microg/L compared to 0.0047 in Germany. BPA is found in fish, feeding bottles, beverage containers and the milk of nursing mothers. Furthermore, BPA levels are 5 times […]

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Conditions: Bisphenol toxicity, Developmental defects, Endocrine dysfunction, Thyroid dysruption

Foods: Fish, Mother's milk

Miscellaneous: African clawed frog (Xenopus laevis), Bisphenol, Embryonic development, Endocrine disruptors, Estrogen, Na/K pump, Na+/K+-ATPase, Otic vesicle, Otolith, Ouabain, Plastic, Thyroid hormone, Xenopus, Zebrafish

Autoimmunity of the Thyroid and Vitiligo.

Posted on January 27, 2014 by Dr. Gary Pack

Vitiligo is a skin disease with typical light patches of skin (depigmentation). Autoimmunity and endocrine diseases are believed to be related to vitiligo, and there is some suggestion that vitiligo is related to thyroid dysfunction also. This study was done to find a relationship between vitiligo and thyroid autoimmunity. The study involved a count of […]

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Conditions: Autoimmune disease, Autoimmune thyroiditis, Depigmentation, Endocrine dysfunction, Goiter, Skin lesions, Vitiligo

Miscellaneous: Autoantibodies, Thyroid gland, Thyroid stimulating hormone, Thyroxine, Triiodothyronine

Disorders from Endocrine-Disrupting Chemicals.

Posted on October 10, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Air fresheners, Alkylphenols, Bisphenol A, Cancer, Cleaning products, Cosmetics, Diabetes, Endocrine-disrupting chemicals, Endocrine dysruptors, Estrogen receptors, Hair dyes, Histone modification, Infertility, Metabolic syndrome, Methylation, Metals, Obesity, […]

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Opiates and Androgen Deficiency.

Posted on August 7, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Analgesia, Androgen deficiency, Dehydroepiandrosterone (DHEA), Depression, Endocrinopathy, Erectile dysfunction, Fatigue, Follicle stimulating hormone, Gonadotrophins, Hair, Hot flashes, Hypogonadism, Libido, Luteinizing hormone, Opioid and opiate, Opioid associated […]

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Conditions: Androgen deficiency, Depression, Endocrine dysfunction, Erectile dysfunction, Fatigue, Hot flashes, Hypogonadism, Libido, Osteopenia, Osteoporosis, Pain

Supplements: Dehydroepiandrosterone (DHEA)

Miscellaneous: Analgesic, Follicle stimulating hormone, Gonadotrophins, Luteinizing hormone, Opiate, Prostate, Testosterone

Bisphenol A and B and Food Packaging.

Posted on June 7, 2011 by Dr. Gary Pack

Large amounts of chemicals Bishpenol A (BPA) and bis(2-ethylhexyl)phthalate (DEHP) are used in the production of plastics and food packaging. These chemicals can result in ‘endocrine disruption’ in humans and animals. The researchers have studied urinary BPA and phthalate to learn more about how these products influence the people who use plastics and food packaging. […]

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Conditions: Bisphenol toxicity, DEHP toxicity, Endocrine dysfunction, Hormonal dysfunction, Sexual dysfunction

Foods: Canned foods

Miscellaneous: Bisphenol, Endocrine disruptors, Food packaging, Packaging, Plastic, Potomac River, Washington DC

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