Library: Viewing all articles on "Uricase (urate oxidase)"

Urate Oxidase Activity in Hominoids and Uric Acid..

Posted on January 25, 2012 by Dr. Gary Pack

Uricase (urate oxidase) is an enzyme that stimulates the oxidation of uric acid to allantoin. The lack of this enzyme in humans results in high uric acid blood levels (hyperuricemia) and gout. Uric acid levels in humans can be 10 times high as in other animals. Reduced urate oxidase activity in humans is due to […]

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Conditions: Cancer, Gout, Gouty arthritis, Hyperuricemia, Mutation, Oxidative damage, Vascular disease

Supplements: Antioxidants, Astragalus (Astragalus membranaceus), Bioflavonoids, White mulberry (Morus alba)

Foods: Black tea (Camellia sinensis), Cocoa

Miscellaneous: Brain, DNA, Polyphenols, Purines, Uric acid (urate), Uricase (urate oxidase), Xanthine oxidase, Xanthine oxidase inhibitors

Hyperuricemia Induces Endothelial Dysfunction.

Posted on December 7, 2006 by Dr. Gary Pack

In humans an enzyme called uricase has mutated, resulting in higher uric acid levels. Hyperuricemia is connected to cardiovascular and kidney disease. This could be the result of reactive oxygen species (ROS) causing damage to the inner endothelial lining of blood vessels. The effect of the enzyme xanthine oxidase is the production of uric acid […]

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