New Treatments of Friedreich Ataxia.

Posted on April 8, 2014 by Dr. Gary Pack

Friedreich ataxia (FRDA) is an autosomal recessive disease in Caucasians. In this disease, there is loss of sensory neurons and degeneration of several nerve pathways of the spinal cord and brain. The result, eventually, is very poor control of voluntary movements. Some patients have loss of white matter of the brain, and some develop an […]

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Conditions: Cardiomyopathy, Cerebellar ataxia, Friedreich's Ataxia, Mitochondrial damage, Neurodegeneration, Oxidation

Supplements: Butyric acid, Carnitine, CoQ-10 (coenzyme Q-10), Creatine, Vitamin E

Miscellaneous: Erythropoietin, Frataxin, Histone deacetylase inhibitors, Idebenone

Micronutrient Deficiencies in Heart Failure.

Posted on November 23, 2009 by Dr. Gary Pack

Heart failure is severely disabling, with high morbidity and mortality. Part of the problem is the heart’s constant need for a very large supply of raw materials to produce a great amount of energy. The heart is “rebuilt” from new chemicals every month. A deficiency of some nutrients is known to cause therapeutic failures, causing […]

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Conditions: Heart failure, Micronutrient deficiencies

Supplements: Carnitine, CoQ-10 (coenzyme Q-10), D-Ribose, Magnesium, Potassium, Propionyl-l-carnitine, Selenium, Taurine, Tyrosine, Vitamin B-1 (thiamine), Vitamin D, Zinc

Foods: Cooking oils, Fish, Legumes, Meat, Milk, Nuts, Poultry, Whole grains

Miscellaneous: LDL-cholesterol, Nutrients

L-Acyl-Carnitine Therapy for Hepatic Encephalopathy.

Posted on May 23, 2008 by Dr. Gary Pack

Advanced liver disease, such as cirrhosis, can cause disability and death from hepatic encephalopathy (HE.) This is characterized by abnormal brain function, from memory loss to coma. Current treatments are hampered by ineffectiveness and side effects. Ammonia from liver dysfunction can pass easily through the blood-brain barrier to cause symptoms of the nervous system. L-acyl-carnitine […]

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Conditions: Cirrhosis, Coma, Hepatic encephalopathy, Liver disease, Liver failure, Memory deficit

Supplements: Acetylcarnitine, Carnitine

Miscellaneous: Acetylcholine, Ammonia, Blood-brain barrier

pH Correction as Therapy for Cachexia.

Posted on April 24, 2008 by Dr. Gary Pack

Cachexia is progressive body wasting with the loss of fat tissue and muscle mass resulting from chronic diseases, such as cancer, congestive heart disease, etc. There is weight loss, weakness, and anemia, but cachexia is not the same as starvation. Cachexia may be present even before the cancer becomes obvious. Acidity can be the cause […]

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Conditions: Acid-base balance, Alkalosis (alkalinity), Cachexia, Cancer, Congestive heart failure, Hyperacidity, Hypoxia

Supplements: Branched-chain amino acids, Carnitine, Eicosapentanoic acid (EPA), Isoleucine, Leucine, Melatonin, Potassium Bicarbonate, Tri-Salts, Valine

Miscellaneous: Muscle, pH, Sodium bicarbonate

Mega-dose Folate for Symptomatic Atherosclerosis.

Posted on January 26, 2007 by Dr. Gary Pack

Dr. Kurt Oster of Germany had a theory, thirty years ago, that xanthine oxidase (XO) enzyme was partly the cause of atherogenesis. He believed that folic acid was a XO inhibitor, mistakenly, and used folic acid to treat circulatory problems. (It was later found that a contaminant in the folic acid actually caused the XO […]

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Conditionally Essential Nutrients in Cardiovascular Disease.

Posted on January 29, 2006 by Dr. Gary Pack

Conditionally essential nutrients (CENs) are compounds produced in our bodies in sufficient amounts under usual conditions. The amount produced is not sufficient under the conditions of disease and these nutrients are required for recovery from disease. The primary CENs for cardiovascular disease are l-arginine, l-carnitine, propionyl-L-carnitine and CoQ-10 (ubiquinone.) These CENs are supported by extensive […]

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Conditions: Angina, Cardiovascular disease, Heart failure, Hyperlipidemia, Hypertension, Intermittent claudication, Myocardial infarction, Nutrient deficiency

Supplements: Alpha lipoic acid, Arginine, Betaine (trimethylglycine) (TMG), Carnitine, Chondroitin sulfate, CoQ-10 (coenzyme Q-10), D-Ribose, Propionyl-l-sulfate, Taurine

Miscellaneous: Conditionally essential nutrients, Nutrients

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