Shilajit and Cognitive Activity.

Posted on December 1, 2014 by Dr. Gary Pack

Shilajit is black/brown powder from north of India which comes from rocks high in the Himalayan mountains. It is widely used in Ayurvedic medicine for rejuvenation and anti-aging, and is enriched in fulvic acid and related chemicals. It is believed to be produced by plant decomposition over centuries. Shilajit has powerful antioxidant activity, and the […]

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Conditions: Allergies, Alzheimer's disease, Cognitive impairment, Diabetes, Digestive problems, Fungal infection, Heavy metal toxicity, Inflammation, Ulcers, Urinary problems

Supplements: Fulvic acid, Shilajit

Miscellaneous: Anti-aging, Ayurvedic medicine, Chile, Himalayas, India, Neuroprotection

Iron Metabolism in Neurodegenerative Diseases.

Posted on April 22, 2014 by Dr. Gary Pack

Poor regulation of iron metabolism is seen in some patients with neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS). Iron transport in and out of brain cells helps maintain cellular balance. Imbalance in iron levels produces neurotoxins, reactive oxygen species and oxidative stress. Iron accumulation in the cells […]

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Conditions: Alzheimer's disease, Amyotrophic lateral sclerosis, Apoptosis, Friedreich's Ataxia, Iron overload, Neurodegenerative disease, Oxidation, Oxidative stress, Parkinson's disease, Thalassemia

Supplements: Iron chelator, Lactoferrin

Miscellaneous: Glial cells, Iron chelator, Reactive oxygen species

Schisandra and Memory Impairment.

Posted on September 24, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. NOTE: Milk thistle is an herb which increases glutathione levels. Cell Guard is a supplement which provides glutathione peroxidase and SOD. KEY WORDS: Alzheimer’s disease, Amyloid, Cognitive enhancer, […]

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Conditions: Alzheimer's disease, Cognitive impairment, Memory deficit

Supplements: Glutathione peroxidase, Lignans, Schizandra (Schizandra chinensis), Superoxide dismutase (SOD)

Miscellaneous: Amyloid, Malondialdehyde (MDA), Memory

Ketogenic Diet for Neurologic Disorders.

Posted on September 19, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Alzheimer’s disease, Autism, Brain cancer, Diet, high fat, low carbohydrate, Energy metabolism, Epilepsy, Headache, Ketogenic diet, Metabolic therapy, Multiple sclerosis, Neurological disease, Neurological disorder, Neurometabolic pathway, […]

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Conditions: Alzheimer's disease, Autism, Brain cancer, Epilepsy, Headache, Multiple sclerosis, Neurologic disease, Neurotrauma, Pain, Parkinson's disease, Sleep

Miscellaneous: Diet, High fat diet, Neuroprotection

Iron and Neurodegeneration.

Posted on July 25, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Alzheimer’s disease, Brain, Friedreich’s Ataxia, Homeostasis, Huntington’s disease, Iron (Fe), Metalloneurobiology, Neurodegeneration, Neuroferritinopathy, Oxidative stress, Parkinson’s disease, Saccharomyces cerevisiae. PMID: 22701145. Summary #828.

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Conditions: Alzheimer's disease, Friedreich's Ataxia, Homeostasis, Huntington's disease, Neurodegeneration, Neuroferritinopathy, Oxidative stress, Parkinson's disease

Supplements: Iron, Saccharomyces cerevisae

Miscellaneous: Brain, Metalloneurobiology

DNA Methylation in Alcoholics and Smokers.

Posted on July 3, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Alzheimer’s dementia, Cancer, Carcinogenesis, Chronic alcoholic, Cigarettes, DNA methylation, Epigenetics, Gene expression, Homocysteine, Multiple sclerosis, S-adenosyl methionine (SAM), Smoke, Tobacco. PMID: 22737275. Summary #800.

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Conditions: Alcoholism, Alzheimer's disease, Cancer, Carcinogenesis, Methylation, Multiple sclerosis, Smokers

Supplements: S-adenosylmethionine (SAMe)

Miscellaneous: DNA, Epigenetics, Gene expression, Homocysteine

Procognitive Activity of Shilajit.

Posted on June 18, 2012 by Dr. Gary Pack

Shilajit is a nutritional supplement from rocky area of northern India and Nepal. It is either a dark brown powder or a thick liquid. It is also found in Russia, Tibet, Afghanistan, and northern Chile (Andean Shilajit). Its action as medicine depends on the origin. It is used in Ayurvedic medicine for rejuvenation. Shilajit is […]

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Conditions: Aging, Alzheimer's disease, Anemia, Arsenic toxicity, Bronchitis, Cognitive impairment, Fungal infection, Genitourinary disease, Immune modulation, Lead toxicity (plumbism), Mercury poisoning, Nephrolithiasis (kidney stones), Neuroprotection

Supplements: Antioxidants, Fulvic acid, Selenium, Shilajit

Miscellaneous: Afghanistan, Chile, Earth, High-altitudes, India, Nepal, ORAC, Sherpas, Tibet, White clover (Trifolium repense)

Antioxidants for Age-Related Macular Degeneration.

Posted on August 19, 2011 by Dr. Gary Pack

The cause of age-related macular degeneration (AMD), a major cause of loss of vision after the age of 60, is unknown. The two types of AMD are wet and dry. In wet AMD, the tissues have characteristic new blood vessels (neovascular). In dry AMD, the tissues are atrophic (shriveled). Recent studies report the following risk […]

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Lithium and CNS Neuroprotection.

Posted on August 5, 2011 by Dr. Gary Pack

Lithium, FDA-approved to treat bipolar disorder (BD), has been USED for 60 years. However, lithium protects and benefits the central nervous system, and there are even indications that lithium can treat other neurodegenerative diseases. Patients with BD who take lithium may experience a reduction of grey matter loss usually seen with that disease. Lithium, also, […]

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Conditions: Alzheimer's disease, Amyotrophic lateral sclerosis, Apoptosis, Autophagy, Cerebellar degeneration, Cognitive impairment, Fragile X syndrome, Huntington's disease, Neurodegenerative disease, Neurogenesis, Neuroprotection, Parkinson's disease, Spinal cord injury, Stroke

Supplements: Lithium

Miscellaneous: Brain-derived neurotrophic factor, Central nervous system

Alzheimer’s Disease, Healthy Fatty Acids and DHA.

Posted on June 19, 2011 by Dr. Gary Pack

DHA treatment may be beneficial for Alzheimer’s disease (AD), which is a neurodegenerative disorder with cognitive and short-term memory impairment. The cause of AD is unknown. Many studies have shown that omega-3 fatty acids reduce the risk of AD. Also, dietary DHA protects learning in rats that have been infused with amyloid-beta (a rat model […]

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