Alzheimer’s Disease and Vascular Dementia Treatment with Huperzine A.

Posted on March 28, 2009 by Dr. Gary Pack

Huperzine A (HupA) comes from the Chinese medicine Huperzia serrata (Qian Ceng Ta). It is an acetylcholinesterase (AChE) inhibitor, which slows AD symptoms. AChEIs have been shown to increase learning and memory in Alzheimer’s disease and vascular dementia (VaD.) (HupA is from lycopodium.) The present study reviews the protective functions of HupA, such as controlling […]

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Conditions: Alzheimer's disease, Apoptosis, Dementia, Inflammation

Supplements: Cell Guard, Glutathione peroxidase, Lycopodium (Huperzia serrata), Superoxide dismutase (SOD)

Miscellaneous: Acetylcholinesterase (ACE) inhibitior, Amyloid

Baicalin is a CNS Prolyl Oligopeptidase Inhibitor.

Posted on November 25, 2008 by Dr. Gary Pack

A chemical called protease prolyl oligopeptidase (POP) is associated with schizophrenia, bipolar affective disorder, and, possibly, Alzheimer’s disease. In a previous study of Chinese herbs, baicalin, a flavonoid, was found to inhibit POP. Baicalin is found in Scutellaria baicalensis (skullcap) root. The authors studied whether baicalin and it’s derivative, baicalein, would cross the intestinal barrier […]

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Conditions: Alzheimer's disease, Angiogenesis, Bipolar depression, Cancer, Neuropsychiatric disease, Schizophrenia

Supplements: Bioflavonoids, Coptis (Coptis chinensis), Quercetin, Skullcap (Scutellaria baicalensis)

Miscellaneous: Berberine, Flavonoids, Luteolin, Propyl oligopeptidase

Toxicology of Mercury.

Posted on April 12, 2007 by Dr. Gary Pack

Chronic low dose mercury exposure and the disease states which result have not been well studied. The role of low dose mercury in chronic disease is controversial, especially in regard to the use of mercury dental amalgams, mercury-containing thiomersal in vaccines and the consumption of mercury containing fish. There has been speculation about the role […]

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Conditions: Alzheimer's disease, Amyotrophic lateral sclerosis, Autism, Mercury poisoning, Multiple sclerosis, Neuroprotection, Parkinson's disease

Supplements: Alpha lipoic acid, Apple pectin, Chelation therapy, Dietary fiber, DMPS, DMSA, Glutathione, N-acetylcysteine (NAC), Selenium, Zinc

Foods: Apple, Fish, Wheat bran

Miscellaneous: Blood-brain barrier, Homocysteine, Ligand, Metabolite, Thiols, Thiomersal, Toxicology, Vaccines

Neuroprotective Effects of Teas and Beta Amyloid.

Posted on March 17, 2006 by Dr. Gary Pack

Teas include a large family of plants which contain beneficial polyphenols. The author studied the theory that tea use protects from age-related neurodegeneration, including Alzheimer’s disease (AD). They studied green and black tea extracts against the toxicity of beta-amyloids. Tea use reduces the risk of developing Parkinson’s disease, stroke and dementia of various causes. Beta-amyloids […]

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Conditions: Alzheimer's disease, Neurodegenerative disease

Supplements: Carnosine

Foods: Black tea (Camellia sinensis), Green tea (Camellia sinensis)

Miscellaneous: Amyloid, Catechins, Flavonoids

Alzheimer’s Type Dementia and Ginkgo Biloba.

Posted on March 15, 2006 by Dr. Gary Pack

The authors did a double-blind, placebo-controlled study of 513 patient’s with Alzheimer’s type dementia. They were placed on Ginkgo biloba 24% extract 120 mg. or 240 mg. per day for 24 weeks. Careful records were kept of the patient’s behavior. There was not marked improvement in the average patient’s condition on the Ginkgo biloba extract. […]

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Conditions: Alzheimer's disease, Neuropsychiatric disease

Supplements: Essential fatty acids, Ginkgo (Ginkgo biloba)

Parkinson’s Disease and Oxidative Neurodegeneration.

Posted on March 10, 2006 by Dr. Gary Pack

Parkinson’s disease (PD) is the most common human movement disorder. Oxidative damage is seen in brain cells (neurodegeneration) in PD. Specific areas of the brain are involved, such as the substantia nigra (SN) of the brain, which is sensitive to oxidation and is often abnormal in PD. Nerves of the SN have dopamine activity. Most […]

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Lithium in Brain Injuries and Neurodegenerative Diseases.

Posted on March 3, 2006 by Dr. Gary Pack

Previous studies in both animals and humans have shown evidence for the benefit of lithium in acute brain injury (such as stroke) and in chronic brain disease (like Parkinson’s disease, Alzheimer’s disease and Huntington’s disease.) Brain injury from lack of oxygen was reduced in rats by 56% when they were pre-treated with lithium. Recent research […]

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Conditions: Alzheimer's disease, Bipolar depression, Brain injury, Huntington's disease, Manic-depression, Oxygen deprivation, Parkinson's disease, Stroke

Supplements: Dehydroepiandrosterone (DHEA), Lithium

Miscellaneous: Brain, Dopamine, Estrogen, Exercise, Gray matter, Neuro-protective, Neurogenesis, Neurotransmitters, Noradrenalin, Radiation, Serotonin

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