Endometriosis Review.

Posted on May 8, 2011 by Dr. Gary Pack

Endometriosis is a pelvic inflammatory disease causing pelvic pain and infertility. It is an estrogen-dependent disease, made worse by increased environmental estrogens. In endometriosis, uterine tissue can be found outside the uterus. Endometriosis occurs during the reproductive years and is progressive. One-half of women with infertility have endometriosis. Kudzu herb produces an isoflavone, puerarin, an […]

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Multiple Sclerosis and Hyperprolactinemia.

Posted on August 20, 2010 by Dr. Gary Pack

Multiple sclerosis (MS) is a disease of relapsing neurologic symptoms with phases of chronic progression. It is a T-cell mediated autoimmune disease. Typical changes of MS are seen in the brain on magnetic resonance imaging (MRI) brain scans. There is some genetic susceptibility for the disease. MS has increased incidence in women. There is evidence […]

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Conditions: Autoimmune disease, Hyperprolactinemia, Multiple sclerosis, Optic neuritis, Prolactinoma

Miscellaneous: Deprenyl, Pituitary gland, Prolactin

Vitex agnus Castus and Prolactinoma.

Posted on May 4, 2010 by Dr. Gary Pack

This article is a response to the article by Gallagher, J., et al, who wrote the article described by Summary 382. That article reviewed the case of a girl with a prolactinoma who improved on an herb, Vitex agnus casti (chasteberry.) This herb is traditionally used for “dysmenorrhea, oligo/amenorrhea, premenstrual syndrome, corpus luteum insufficiency, infertility, […]

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Conditions: Amennorrhea, Galactorrhea, Hyperprolactinemia, Mastalgia, Prolactinoma

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Phenylalanine, Tyrosine

Miscellaneous: Dopamine agonists, Pituitary gland

Maca, Sexual Performance and Erectile Dysfunction.

Posted on April 16, 2010 by Dr. Gary Pack

Lepidium meyenii (maca) is a member of the Brassica (mustard) family from high in the Andes Mountains. The root has long been used as an aphrodisiac or for fertility. In this study, maca was used by Caucasian males with mild erectile dysfunction (ED). The subjects received either 2,400 mg. of dry maca extract or placebo […]

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Conditions: Erectile dysfunction, Hyperprolactinemia

Supplements: Maca (Lepidium meyenii)

Foods: Mustard greens

Miscellaneous: Brassica species

Gluten-Free Diet: High Sugar, Low Fibre and Low Mineral Intake.

Posted on April 8, 2010 by Dr. Gary Pack

The must successful treatment for celiac disease (CD) is a life-long gluten-free diet (GFD.) There are few studies to determine the composition of the GFD. Food questionnaires were used to study the diets of patients with CD on a GFD to compare with people who were not on a GFD. Detailed food diaries were kept. […]

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Conditions: Aging, Autoimmune disease, Celiac disease, Hyperprolactinemia

Supplements: Fiber, Folic acid (folate), Iron, Magnesium, Manganese, Selenium, Zinc

Foods: Beans, Potatoes, Pulses, Sweet potatoes

Miscellaneous: Gluten-free diet, Nutrients, Prolactin

Biomarkers in Autoimmune Diseases..

Posted on December 20, 2008 by Dr. Gary Pack

Autoimmune diseases can result from hormonal, immune and metabolic processes. This study was done to determine levels of prolactin (PRL), ferritin, vitamin D and tumor marker tissue polypeptide antigen (TPA) in autoimmune diseases, such as systemic lupus erythematosus (SLE), systemic sclerosis (SSC), rheumatoid arthritis (RA), polymyositis (PM), dermatomyositis (DM), multiple sclerosis (MS), antiphospholipid syndrome and […]

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The Role of Prolactin- and Endometriosis-Associated Infertility.

Posted on February 15, 2008 by Dr. Gary Pack

This is a review of hyperprolactinemia or hyperprolactinaemia (high blood prolactin) in endometriosis-related infertility. The fact of their connection is known; but, the definite cause of the relationship between high prolactin (PRL) levels and infertility is not known. This article is a review of the current literature on the subject. PRL is known to have […]

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Conditions: Breastfeeding, Endometriosis, Hyperprolactinemia, Infertility

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Phenylalanine, Tyrosine

Miscellaneous: 5-lipoxygenase inhibitors, Dopamine agonists, Pituitary gland, Prolactin

Chaste Tree (Vitex Agnus-Castus.)

Posted on January 10, 2008 by Dr. Gary Pack

Chaste tree (Vitex agnus castus) fruit extracts have been shown to reduce premenstrual symptoms of breast pain and swelling (mastodynia) and other premenstrual mental and physical symptoms. Large amounts of prolactin are produced premenstrually and are probably the cause of mastodynia. Prolactin levels are increased by pituitary tumors(prolactinomas) during stress and in certain stages of […]

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Conditions: Autoimmune disease, Depression, Hyperprolactinemia, Irritability, Premenstrual syndrome, Prolactinoma, Sleep, Stress

Supplements: Chasteberry (Vitex agnus castus), Coleus (Coleus forskohlii)

Miscellaneous: Clerodadienols, Diterpene, Dopamine, Dopamine agonists, Forskolin (Coleonol), Pituitary gland, Prolactin

Hyperprolactinemia in Breast and Prostate Cancer.

Posted on June 13, 2007 by Dr. Gary Pack

Prolactin is a hormone produced by the pituitary gland that is responsible for breast development and lactation, which acts both as a hormone and as a cytokine. Cytokines “can activate signalling pathways that promote cell growth and survival with increasing evidence of a role in cancers, such as breast and prostate.” Symptoms of high prolactin […]

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Serotonin Dysfunction in Pathological Gamblers.

Posted on February 15, 2007 by Dr. Gary Pack

Serotonin (5-hydroxytryptamine or 5-HT) agonists mimic and enhance the effect of 5-HT. A 5-HT agonist produces a “high” and a craving response in some people with impulse disorders and some substance abuse disorders. The present study was done to evaluate 5-HT metabolism in gamblers. After a dose of a 5-HT agonist, the subjects were tested […]

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Conditions: Cancer, Hyperprolactinemia, Impulse disorders, Parkinson's disease, Pathologic gambler, Substance abuse

Supplements: 5-OH tryptophan, Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Tryptophan, Tyrosine

Miscellaneous: 5-lipoxygenase inhibitors, Dopamine agonists, Serotonin agonists

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