Endothelial Dysfunction in Diabetic Erectile Dysfunction.

Posted on January 25, 2007 by Dr. Gary Pack

Erectile dysfunction (ED) is very common in diabetes mellitus. ED refers to the “inconsistent inability to achieve and maintain penile erection sufficient for adequate sexual relations.” ED is associated with diabetes, aging, high blood cholesterol (hypercholesterolemia,) hypertension, sedentary life style and cigarette smoking. ED seems to be mainly due to inability of the inner lining […]

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Hyperuricemia Induces Endothelial Dysfunction.

Posted on December 7, 2006 by Dr. Gary Pack

In humans an enzyme called uricase has mutated, resulting in higher uric acid levels. Hyperuricemia is connected to cardiovascular and kidney disease. This could be the result of reactive oxygen species (ROS) causing damage to the inner endothelial lining of blood vessels. The effect of the enzyme xanthine oxidase is the production of uric acid […]

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Uric Acid in Fructose-Induced Metabolic Syndrome.

Posted on December 7, 2006 by Dr. Gary Pack

The metabolic syndrome is the cause of a worldwide epidemic consisting of: Obesity, poor tolerance to glucose, hyperinsulinemia, hyperuricemia (high serum uric acid,) hypertriglyceridemia, and hypertension, which are all risk factors for cardiovascular disease. The metabolic syndrome is seen in 27% of the population of the United States and the diagnosis of metabolic syndrome triples […]

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Acid Diet, Potassium Citrate and Bone Mass in Osteopenia.

Posted on October 26, 2006 by Dr. Gary Pack

Osteoporosis is becoming a significant problem for our aging population. It is believed that osteoporosis is increased by our high protein diets, causing increased acid formation and reduced potassium consumption. (Not all studies agree with these statements.) The acid load of the Western diet is 25-125 mmol./day of acid for the person’s life. This results […]

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Conditions: Acidosis (acidity), Aging, Blood pressure, Hypertension, Osteopenia, Osteoporosis, Postmenopausal

Supplements: Calcium carbonate, Damiana (Turnera diffusa), Potassium, Potassium chloride, Potassium citrate, Vitamin D-3

Miscellaneous: Anti-aromatase, BMD (bone mineral density), Western diet

Menopause: Oxygen Stress and Dietary Antioxidants.

Posted on September 28, 2006 by Dr. Gary Pack

Menopause is a permanent loss of menstruation after a period of amenorrhea (abnormal stoppage of the menstrual periods) lasting more than one year. The usual range of age of onset is age 40 to 55 and symptoms of menopause include hot flashes, arteriosclerosis, and deterioration of the skin suggestive of estrogen deficiency. Hormone replacement therapy […]

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Paleolithic Diet Versus the Western Diet.

Posted on September 28, 2006 by Dr. Gary Pack

Environmental changes, including diet and lifestyle, which took place 10,000 years ago have been too recent for the human genome to make a proper adjustment. As a result “diseases of civilization” have emerged. The types of foods and food processing developed in the recent Neolithic and Industrial Periods have changed the following elements of our […]

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Conditions: "Diseases of Civilization", Acid-base balance, Aging, Asthma, Cancer, Cardiovascular disease, Coronary heart disease, Diabetes, Dyslipidemia, Hypertension, Insulin resistance, Kidney stones, Metabolic acidosis, Metabolic syndrome, Obesity, Osteoporosis, Renal (kidney) disease

Supplements: Calcium, Fiber, Magnesium, Omega-3 fatty (linolenic) acid, Omega-6 fatty (linoleic) acid, Vitamin A, Vitamin B-6 (pyridoxine), Zinc

Foods: Alcohol, Almonds, Beer, Cereals, Cottonseed oil, Dairy, Fermented foods, Flax seed, Fructose, Glucose, Grains, High fructose corn syrup, Margarine, Monounsaturated fatty acid, Olives, Polyunsaturated oil, Salt, Sesame seeds, Sucrose, Sugars, Trans fats, Vegetable oils, Walnuts, Wild animals, Wild plants, Wine

Miscellaneous: Diet, Evolutionary discordance, Genome, Hunter-gatherer diet, Lifestyle, Na/K, Neolithic diet, Nutrients, Paleolithic diet

The Clinical Significance of Endothelial Dysfunction.

Posted on May 11, 2006 by Dr. Gary Pack

Endothelial dysfunction is the start of the process of damage to the blood vessels of the body resulting in arteriosclerosis. Risk factors that increase endothelial dysfunction include hypertension, diabetes, abnormal blood fats and smoking. Endothelial dysfunction is first manifest by poor relaxation of the inner endothelial lining of blood vessels. This failure has been found […]

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Conditions: Arteriosclerosis (atherosclerosis), Diabetes, Endothelial dysfunction, Hypertension, Smokers

Supplements: Arginine

Miscellaneous: Anti-inflammatory, Anti-thrombotic, Endothelial progenitor cells, Exercise, HDL-cholesterol, Nitric oxide (NO), Nitric oxide synthetase, Tetrahydrobiopterin

Supplemental KCl and KHCO3.

Posted on April 29, 2006 by Dr. Gary Pack

The modern diet contains much less potassium, a deficiency in bicarbonates and an excess of sodium chloride (NaCl) compared to the diet of our prehistoric ancestors. The result of these dietary changes is that many modern people maintain a low-grade systemic acidosis especially as they age. Acidosis can be corrected by introducing high levels of […]

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Conditions: Acidosis (acidity), Aging, Hypertension, Kidney stones, Osteoporosis, Stroke

Supplements: Potassium

Foods: Fruits, Vegetables

Miscellaneous: Diet, Postmenopausal, Potassium bicarbonate, Potassium chloride, Potassium citrate

Potassium in Preventing and Treating High Blood Pressure..

Posted on April 25, 2006 by Dr. Gary Pack

According to the authors, supplementation with oral potassium results in a lower blood pressure in humans. The purpose of this study was to demonstrate potassium’s effect on high blood pressure by making an analysis of 33 previous trials, involving 2609 patients, that used potassium to treat high blood pressure. In all but two of the […]

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Conditions: Alcohol consumption, Exercise, Hypertension, Kidney (renal) failure

Supplements: Potassium

Miscellaneous: Alcohol, Paleolithic diet, Sodium

Inhibition of Platelet Aggregation by Nettles Extract.

Posted on April 21, 2006 by Dr. Gary Pack

Platelets are the cells of the blood that make clotting possible and prevent hemorrhage. Platelet over activity increases thrombosis or clogging of arteries and plays a part in the development of atherosclerosis. Rat platelets were studied in the laboratory by chemically inducing aggregation or clumping of platelets. Various concentrations of nettles (Urtica dioica) were applied […]

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Conditions: Angina, Arteriosclerosis (atherosclerosis), Cardiovascular disease, Diabetes, Hemorrhage, Hypertension, Myocardial infarction, Peripheral artery disease, Platelet clumping, Platelet overactivity, Stroke, Thrombosis

Supplements: Bioflavonoids, Nettles (Urtica dioica)

Miscellaneous: Clot, Flavonoids, Platelet inhibition

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