Potatoes, Tryptophan and the Kynurenine Path.

Posted on January 9, 2017 by Dr. Gary Pack

Trypotophan amino acid is metabolized by a series of chemical reactions called the kynurenine pathway. One product is kynurenic acid (KA), which protects the nervous system, reduces inflammation, reduces tissue oxidation and may even prevent cancer. KA is anticonvulsant and has functions in the gastrointestinal tract. The blood-brain barrier (which blocks passage of chemicals from […]

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Conditions: Cancer, Inflammation, Neuroprotection, Oxidation, Seizures

Supplements: Pollen, Propolis, St. John's Wort (Hypericin perforatum), Tryptophan, Vitamin C (ascorbic acid)

Foods: Broccoli, Honey, Potato crisps, Potato flour, Potatoes, Sweet potatoes

Miscellaneous: Amino acid, Anti-convulsants, Anti-inflammatory, Blood-brain barrier, Kyneurenic acid, Kynurenine pathway, Starch, Sugar

Cannabidiol.

Posted on September 18, 2015 by Dr. Gary Pack

Marijuana (Cannabis sativa) has been used for centuries as an herb to treat pain. It can be smoked (inhaled) and eaten (oral). Recent evidence for benefits of this herb have been shown for pain of nerve origin associated with HIV and spasticity with multiple sclerosis. The major non-psychoactive component of marijuana is cannabidiol (CBD). CBD […]

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Conditions: Epilepsy, Nerve pain, Pain, Seizures

Supplements: Calcium, Cannabidiol (CBD) oil, Potassium

Miscellaneous: Calcium channel blockers, Calcium channels, Marijuana (Cannabis sativa), Psychoactive, Voltage-gated calcium channels

Increasing Urinary Elimination in Acute Poisoning.

Posted on July 6, 2015 by Dr. Gary Pack

The outcomes of patients with accidental and intentional poisonings were studied in Rio Grande de Sul, a state in Brazil. Cases reported as severe to the Poisoning Control Center were reviewed, and poisonings were due to drugs and pesticides. Acute poisonings were most often due to medications, such as anticonvulsants, antidepressants, barbiturates, sedatives, and antipsychotics. […]

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Conditions: Accidents, Alkalosis (alkalinity), Depression, Dialysis, Glyphosate (Roundup) poisoning, Kidney transplant, Poisoning, Seizures, Suicide, Vomiting

Supplements: Charcoal

Miscellaneous: Anticonvulsant, Antidepressant, Bipyridyl, Chelation, Chloramphenicol, Hyperbaric oxygen, Nephrologist, Organophosphates, Paraquat, Pesticides, Phenobarbital, Roundup herbicide (glyphosate), Zenobiotics

Aluminum and Neurodegenerative Disease.

Posted on April 20, 2015 by Dr. Gary Pack

Although aluminum (Al) is the most common mineral in the Earth’s crust, it seems to have no useful function in plants or animals. Al was unknown in our environment until extraction for industrial uses began in the 1820’s. Humans get Al internally mostly from food. Now it is used in “food processing, manufacturing, medicines, cosmetics, […]

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Alpha Lipoic Acid in Diabetic Neuropathy.

Posted on March 19, 2015 by Dr. Gary Pack

Diabetes mellitus (DM), a very common disease around the world, is a complicated variety of neuropathies or damaged nerves. This is most common in longer nerves of the body, causing “hot, burning, electric, sharp, achy and tingling sensations in a stocking-glove distribution”. Patients may complain of numbness and trouble walking, and the cause is believed […]

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Conditions: Depression, Diabetes, Hyperglycemia, Oxidation, Pain, Peripheral neuropathy, Polyneuropathy, Seizures

Supplements: Alpha lipoic acid, Antioxidants, Glutathione, Vitamin C (ascorbic acid), Vitamin E

Foods: Glucose

Miscellaneous: Anticonvulsant, Antidepressant, Antioxidant, Opiate

Bacopa, GABA and the Brain.

Posted on September 20, 2013 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Gamma amino butyric acid (GABA). Bacopa (Bacopa monnieri). Bacoside-A. Cerebral cortex. Epilepsy. Neurotransmitter. Seizures. To order the above products call 415-863-0620 and ask for “supplements”. […]

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Conditions: Epilepsy, Seizures

Supplements: Bacopa (Bacopa monniera), Gamma amino butyric acid (GABA)

Miscellaneous: Bacosides A and B, Cerebral cortex, Neurotransmitters

Ketogenic Diet.

Posted on September 30, 2012 by Dr. Gary Pack

To read the author’s abstract of the article, click on the title of the article. Then, to read the full article, click on the full text icon. KEY WORDS: Adenosine, Anticonvulsant, Anti-epileptogenic, Bioenergetic reserves, Brain function, Elevated fatty acid, Epilepsy, GABA neurotransmission, Ketogenic diet, Ketosis, Metabolic changes, Mitochondria, Neuroinflammation, Neurological disorders, Neuroprotective, Reduced glucose level. […]

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Conditions: Bioenergetic balance, Epilepsy, Hyperlipidemia, Ketosis, Neuroinflammatory disease, Neurological damage, Seizures

Supplements: Gamma amino butyric acid (GABA)

Miscellaneous: Adenosine, Anticonvulsant, Ketogenic diet

Nigella Sativa (Black Cumin Seed) in Seizures.

Posted on December 14, 2010 by Dr. Gary Pack

Better treatments are needed for seizures in childhood. Many children have poorly controlled seizures on medications (15% of children) and many have excessive side effects on medications. Black cumin seed (Nigella sativa) is anticonvulsant, in addition to many other effects. The plant is native in Iran and is part of Islamic practice. In this study, […]

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Conditions: Arteriosclerosis (atherosclerosis), Cancer, Rheumatoid arthritis, Seizures

Supplements: Black seed (Nigella sativa), Vitamin K

Miscellaneous: Anticonvulsant, Ranunculaceae fam., Thymoquinone, Valproic acid (Valproate)

Bacopa and Epilepsy-Related Behavioral Deficits.

Posted on November 10, 2010 by Dr. Gary Pack

Bacopa monnieri is an Ayurvedic herbal treatment used to improve “concentration, comprehension, recall and alertness.” The Sanskrit name for Bacopa is Brahmi, which is, also, the Sanskrit name for Centella asiatica (gotu kola.) Bacopa is an antioxidant. This review covers the use of Bacopa in epilepsy related problems. Bacopa contains numerous chemicals including alkaloids and […]

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Conditions: Attention deficit disorder, Cognitive impairment, Epilepsy, Seizures, Stress

Supplements: Bacopa (Bacopa monniera), Gamma amino butyric acid (GABA), Gotu kola (Centellla asiatica)

Miscellaneous: Acetylcholine, Adaptogens, Alkaloids, Anticonvulsant, Antioxidant, Ayurvedic medicine, Bacosides A and B, Glycosides, Serotonin

Oral L-Glutamine Increases GABA Levels.

Posted on April 10, 2008 by Dr. Gary Pack

Adequate levels of two neurotransmitters, gamma-aminobutyric acid (GABA) and glutamate, are dependent on an adequate supply of glutamine to the central nervous system (brain and spinal cord). Glutamate does not cross the blood-brain barrier, but glutamine does. Glutamine treatment increases plasma and brain levels of glutamine, and serves as raw material for the production of […]

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Conditions: Ammonia toxicity, Anxiety, Confusion, Hepatic encephalopathy, Liver failure, Schizophrenia, Seizures

Supplements: Gamma amino butyric acid (GABA), Glutamine, Tryptophan, Tyrosine

Miscellaneous: Blood-brain barrier, Catecholamines, Glutamate, Neurotransmitters, Serotonin

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