Neuroactive Steroids, Mood Stabilizers, Neuroplasticity and Lithium.

Posted on February 14, 2008 by Dr. Gary Pack

Neuroactive steroids (NS) protect our nervous systems, promote the growth of new nerve cells and protect our nerve cells from apoptosis. NS are altered in people with bipolar disorder. The authors theorized that the drug Valproate and lithium could prevent apoptosis and that drugs used for manic-depressive disorder might work by increasing levels of NS. […]

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Conditions: Anxiety, Apoptosis, Bipolar depression, Neuroplasticity, Seizures, Suicide

Supplements: Gamma amino butyric acid (GABA), Lithium

Miscellaneous: Allopregnanolone, Anticonvulsant, Gray matter, Neuroprotection, Pregnenolone, Valproic acid (Valproate)

Anticonvulsant Effects of Passionflower.

Posted on December 17, 2007 by Dr. Gary Pack

Passionflower (Passiflora incarnata) is an herb used in traditional medicine for anxiety, insomnia and seizures. Testing has shown sedative and anti-anxiety effects. Passiflora contains alkaloids, phenols, flavonoids (vitexin and rutin), etc. A specific extract of passionflower (Pasipay) is used for opioid withdrawal. The current pharmacologic treatment of seizures has many side effects and 30% of […]

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Conditions: Absence seizures, Anxiety, Insomnia, Opium dependency, Seizures

Supplements: Black seed (Nigella sativa), Coriander (Coriandrum sativa), Gamma amino butyric acid (GABA), Passionflower (Passiflora incarnata), Rutin

Miscellaneous: Alkaloids, Anti-anxiety, Anti-convulsants, Benzodiazepine, Flavonoids, GABA inhibitor, Phenols, Valium (diazepam)

Anticonvulsant Effects of Nigelia Sativa Seeds.

Posted on December 13, 2007 by Dr. Gary Pack

Thymoquinone is the major component of the seeds of black cumin (Nigelia sativa), which grows in countries around the Mediterranean Sea, is part of the Ranunculaeae family. It has been shown to be antihistaminic, antihypertensive, analgesic, antioxidant, anti-inflammatory, antibacterial, antifungal, antihelminic and antitumour. The major effects are believed to be due to quinones, of which […]

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Conditions: Bacterial infection, Cancer, Fungal infection, Hypertension, Inflammation, Seizures

Supplements: Black seed (Nigella sativa), Gamma amino butyric acid (GABA)

Miscellaneous: Analgesic, Anti-inflammatory, Antibacterial, Anticancer, Antifungal, Antihelminic, Antihistaminic, Antihypertensive, Antioxidant, Mediterranean Sea, Muscle, Ranunculaceae fam., Thymoquinone

Gamma-Aminobutyric Acid (GABA)-Monograph.

Posted on December 13, 2007 by Dr. Gary Pack

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the central nervous system (CNS), and is necessary to balance the natural excitatory nature of the CNS. GABA helps prevent stress, irritability, seizures, insomnia and movement disorders. Inadequate GABA is seen in psychiatric and neurologic diseases, such as anxiety, insomnia, depression and epilepsy. Low GABA levels […]

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Conditions: Anxiety, Depression, Epilepsy, Insomnia, Irritability, Movement disorders, Parkinson's disease, Post-partum depression, Seizures, Stress, Tourette's syndrome

Supplements: Gabapentin, Gamma amino butyric acid (GABA), Glutamine, Lactobacillus hilgardii, Phosphatidylserine (PS), Valerian (Valeriana officinalis)

Foods: Kimchi

Miscellaneous: Central nervous system, Glutamic acid, Neurotransmitters, Yoga

Coleus Forskohlii, Monograph.

Posted on November 6, 2007 by Dr. Gary Pack

Coleus forskohlii is a plant used medicinally in Hindu and Ayurvedic medicine. Traditional uses have been for hypertension, congestive heart failure, seizures and other diseases. The active ingredient is forskolin, which clinical studies suggest may be beneficial in asthma, angina, psoriasis and prevention of cancer metastases. The plant Coleus f. is a colorful member of […]

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