Premenstrual Syndrome: From Etiology to Treatment.

Posted on January 13, 2007 by Dr. Gary Pack

Physical symptoms during the premenstrual period are referred to as premenstrual syndrome (PMS) and mental symptoms in the premenstrual period are referred to as premenstrual dysphoric disorder (PMDD). The symptoms alter the person’s daily activities. The American College of Obstretics and Gynecology says that the diagnosis of PMS is made “if at least one mental […]

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Exercise Thermoregulation and Hyperprolactinemia.

Posted on January 12, 2007 by Dr. Gary Pack

Central fatigue is a combination of symptoms originating in the central nervous system and can be related to heavy exercise, especially in the heat. The symptoms of central fatigue include the following: 1. Problems controlling temperature. 2. Behavior changes. 3. Mood changes. 4. Problems with mental arousal. 5. Loss of motivation. Central nervous pathways of […]

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Conditions: Central fatigue, Exercise, Hyperprolactinemia, Hyperthermia

Miscellaneous: Brain, Dopamine, Hypothalamus, Neurotransmitters, Pituitary gland, Prolactin, Serotonin

Prolactin-Receptor Antagonists for Hyperprolactinemia?

Posted on December 8, 2006 by Dr. Gary Pack

Prolactin is a hormone and a polypeptide (protein). The hormonal effects are related to reproduction and milk production. Hyperprolactinemia or hyperprolactinaemia (high prolactin levels) from any cause can be symptomatic, especially by causing problems with reproduction. Dopamine is a neurotransmitter which suppresses pituitary prolactin production. Dopamine is used for this clinically through the action of […]

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Conditions: Autoimmune disease, Breast cancer, Cancer, Hyperprolactinemia, Prostate cancer, Reproductive disfunction

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus)

Miscellaneous: 5-lipoxygenase inhibitors, Dopamine, Dopamine agonists, Neurotransmitters, Pituitary gland, Prolactin, Prolactin-receptor antagonists, Serotonin

Tetrahydrobiopterin Deficit in Schizophrenia.

Posted on July 30, 2006 by Dr. Gary Pack

This study by Richardson, et al, was done to test the relationship between blood levels of tetrahydrobiopterin (BH4) and schizophrenia. BH4 is a vital chemical cofactor necessary for the body for making the following neurotransmitters: Dopamine (DA.) Noradrenaline (NA.) Serotonin (5-HT.) Nitric oxide (NO.) Glutaminergic system stimulation. Phenylalanine blood levels were also tested because phenylalanine […]

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Conditions: Schizophrenia

Supplements: Phenylalanine, Tetrahydrobiopterin (BH4)

Miscellaneous: Dopamine, Neurotransmitters, Noradrenalin, Serotonin

Parkinson’s Disease and Oxidative Neurodegeneration.

Posted on March 10, 2006 by Dr. Gary Pack

Parkinson’s disease (PD) is the most common human movement disorder. Oxidative damage is seen in brain cells (neurodegeneration) in PD. Specific areas of the brain are involved, such as the substantia nigra (SN) of the brain, which is sensitive to oxidation and is often abnormal in PD. Nerves of the SN have dopamine activity. Most […]

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Lithium in Brain Injuries and Neurodegenerative Diseases.

Posted on March 3, 2006 by Dr. Gary Pack

Previous studies in both animals and humans have shown evidence for the benefit of lithium in acute brain injury (such as stroke) and in chronic brain disease (like Parkinson’s disease, Alzheimer’s disease and Huntington’s disease.) Brain injury from lack of oxygen was reduced in rats by 56% when they were pre-treated with lithium. Recent research […]

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Conditions: Alzheimer's disease, Bipolar depression, Brain injury, Huntington's disease, Manic-depression, Oxygen deprivation, Parkinson's disease, Stroke

Supplements: Dehydroepiandrosterone (DHEA), Lithium

Miscellaneous: Brain, Dopamine, Estrogen, Exercise, Gray matter, Neuro-protective, Neurogenesis, Neurotransmitters, Noradrenalin, Radiation, Serotonin

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