Low HDL-Cholesterol Management.

Posted on October 16, 2013 by Dr. Gary Pack

Statin drugs are credited with a significant reduction of cardiovascular disease over the past 20 years. However, even when LDL (low-density lipoprotein cholesterol) has been properly reduced, heart attacks still occur. Additional targets besides LDL-lowering must be explored, such as HDL. HDL (high-density lipoprotein cholesterol), when elevated, is associated with a lower incidence of heart […]

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Apoptosis and Necrosis.

Posted on October 13, 2012 by Dr. Gary Pack

Apoptosis is an “intricate, programmed pathway of cell death”, which is considered to be a more natural form of cell death as compared to necrosis. In apoptosis, the following steps are seen: Cell shrinkage. Condensation of nucleus contents. DNA fragmentation. In contrast to apoptosis, cell death seen with injury to the cell (necrosis) includes swelling […]

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Conditions: Apoptosis, Cell death, DNA damage, Inflammation, Necrosis

Supplements: Phosphatidylserine (PS)

Miscellaneous: Phospholipids, Sphingomyelin, Tumor Necrosis Factor (TNF)

Fatty Acids from Dietary Sources.

Posted on August 8, 2011 by Dr. Gary Pack

Lipids, proteins, and carbohydrates are the major three components of animal and plant tissues. Lipids include a variety of sources of energy for the human body, including fats and triglycerides. Fatty acids, a major component of lipids, provide up to 30% of human energy and are an important component of cell membranes. Fats are stored […]

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Omega-3, DHA, and EPA for Cognition, Behavior, and Mood.

Posted on March 14, 2009 by Dr. Gary Pack

Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are omega-3 fatty acids which are conditionally beneficial. They function on cell membranes where they are attached to phospholipids. Cell membranes are the “pacemakers of metabolism.” Increasing the unsaturated fatty acids in the membranes improves “fluidity” of cell membranes and improves cellular functioning. This is important in such […]

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Milk Thistle Phytosome.

Posted on November 7, 2007 by Dr. Gary Pack

Milk thistle (Silybum marianum), an anti-oxidant, contains flavonoids that protect the liver. The liver detoxifies hormones and other chemicals produced in the body and is an easy target for damage by any toxins ingested. Silymarin is the active extract of Milk thistle which contains the following flavonoids: Silibin, silydianin and silychristin. Silibin is a flavonolignan. […]

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Conditions: Alcoholic hepatitis, Liver protection, Liver toxicity, Viral hepatitis

Supplements: Antioxidants, Bioflavonoids, Curcumin, Glutathione, Grape seed extract, Green tea, Lignans, Milk thistle (Silybum marianum), Phosphatidylcholine, Phytosomes, Silibinin, Silymarin

Foods: Soy

Miscellaneous: Phospholipids

Antioxidant and Anti-Inflammatory Activity of Andrographis.

Posted on May 29, 2007 by Dr. Gary Pack

An oxygen free radical (OFR) is the form of oxygen that has one unpaired electron and is very reactive. There are other forms of highly reactive oxygen, which do not have unpaired electrons known as reactive oxygen species (ROS.) ROS include singlet oxygen, hydrogen peroxide and hydroxyl radicals, which are constantly being produced by ionizing […]

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Lutein Bioavailability from Lutein-Enriched Eggs.

Posted on October 6, 2006 by Dr. Gary Pack

There are a number of carotenes, including beta-carotene and one of the benefits of fruits and vegetables is in the carotene content. Another carotene is lutein, which has been shown to be of protective benefit in age-related macular degeneration (ARMD). ARMD is inversely related to lutein levels in our diets, blood, and the macula (the […]

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Conditions: Age-related macular degeneration

Supplements: Antioxidants, Carotenes, Carotenoids, Lutein

Foods: Chicken, Eggs, Fruits, Spinach, Vegetables

Miscellaneous: Cholesterol, Lipids, Macula, Phospholipids, Triglycerides

Peripheral Neuropathy and Neuropathic Pain.

Posted on October 3, 2006 by Dr. Gary Pack

Peripheral neuropathy is most commonly caused by diabetes mellitus and neuropathy doubles the risk of amputation in diabetics. Evening primrose oil is a source of gamma-linolenic acid (GLA.), which leads to more eicosanoids that dilate blood vessels in the diabetic. Eicosanoids also cause an improvement of nerve function as evidenced by improved nerve conduction testing. […]

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