Parkinson’s Disease and Molecular Hydrogen.

Posted on May 12, 2017 by Dr. Gary Pack

Melanin is a pigment located in the skin and in a deep part of the brain called the Substantia Nigra (SN). This area of the brain deteriorates in Parkinson’s Disease (PD). Melanin production* deteriorates in the SN as PD progresses, and this may be a cause for progression of the disease. Melanin may be able […]

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Conditions: Environmental toxicity, Parkinson's disease

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Glucosamine, Iron, Tetrahydrobiopterin (BH4), Tyrosine, Velvet bean (Mucuna pruriens)

Miscellaneous: Free radicals, l-DOPA, Melanin, Molecular hydrogen, Substantia nigra, Tyrosine hydroxylase

Natural Promotion of p53 Protein Activity.

Posted on February 10, 2016 by Dr. Gary Pack

TP53 is a “tumor suppressor gene” in cells which produces a protein called p53. It is a tumor inhibitor which triggers apoptosis in abnormal cells, such as cancer cells. It has been said that p53 protein is the ultimate tumor suppressor in the human body, and that a cell which has normal p53 will not […]

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Dopamine Hypothesis of Addiction.

Posted on July 31, 2012 by Dr. Gary Pack

Dopamine (DA), a neurotransmitter*, is involved with brain activity in drug abuse and other addictions. The activity of DA neurons in the brain is reduced in alcohol, opiate and cannabinoid-dependent rats. DA activity is depressed in an area of the brain called the nucleus accumbens in drug-dependent rodents. These deficiencies contribute to the ‘dopamine-impoverished brain’ […]

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Seabuckthorn Contains Beta-Sitosterol.

Posted on June 6, 2011 by Dr. Gary Pack

Plant sterols (phytosterols) can be removed from many plants. Beta-sitosterol can be extracted from Sea buckthorn seeds. Such natural chemicals have medicinal effects which are more effective with fewer side effects than synthetic chemicals. Such sterols are found in saw palmetto leaves, dandelion leaves and chaste tree leaves. Plant sterols are used in cancer treatment. […]

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Conditions: Cancer, Hypercholesterolemia

Supplements: Beta-sitosterol, Chasteberry (Vitex agnus castus), Dandelion (Taraxicum officinale), Plant sterols (Phytosterols), Saw palmetto (Serenoa repens), Seabuckthorn (Hippophae rhamnoides)

Foods: Cooking oils

Endometriosis Review.

Posted on May 8, 2011 by Dr. Gary Pack

Endometriosis is a pelvic inflammatory disease causing pelvic pain and infertility. It is an estrogen-dependent disease, made worse by increased environmental estrogens. In endometriosis, uterine tissue can be found outside the uterus. Endometriosis occurs during the reproductive years and is progressive. One-half of women with infertility have endometriosis. Kudzu herb produces an isoflavone, puerarin, an […]

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Pregnancy, Prolactin and White Matter Regeneration.

Posted on November 19, 2010 by Dr. Gary Pack

There is a search for chemicals, oral or injectable, which will cross the blood-brain barrier to the brain to support brain repair. The authors have reported the benefits of prolactin (PRL) and luteinizing hormone on the development of new neurons (neurogenesis.) The present report is on the benefit of PRL in pregnancy on neurogenesis and […]

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Prolactinoma Masked by a Herbal Remedy.

Posted on May 4, 2010 by Dr. Gary Pack

The authors report a patient who came to a women’s clinic with signs of a prolactin producing brain tumor of the pituitary. When she first came to the women’s clinic, she had a history of infrequent menstrual periods leading to amenorrhea (absence of periods). Her breasts began producing milk, although she was not pregnant (galactorrhea.) […]

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Conditions: Amennorrhea, Galactorrhea, Pituitary adenoma, Prolactinoma

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Phenylalanine, Tyrosine

Miscellaneous: Dopamine agonists, Pituitary gland, Prolactin

Vitex agnus Castus and Prolactinoma.

Posted on May 4, 2010 by Dr. Gary Pack

This article is a response to the article by Gallagher, J., et al, who wrote the article described by Summary 382. That article reviewed the case of a girl with a prolactinoma who improved on an herb, Vitex agnus casti (chasteberry.) This herb is traditionally used for “dysmenorrhea, oligo/amenorrhea, premenstrual syndrome, corpus luteum insufficiency, infertility, […]

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Conditions: Amennorrhea, Galactorrhea, Hyperprolactinemia, Mastalgia, Prolactinoma

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Phenylalanine, Tyrosine

Miscellaneous: Dopamine agonists, Pituitary gland

Autoimmune Etiology of Generalized Vitiligo.

Posted on October 31, 2009 by Dr. Gary Pack

Vitiligo is an autoimmune disease with the skin melanocyte cells being the immune target. The result is poor skin pigmentation (hypopigmentation.) The melanocyte cells are especially sensitive to immune attack. They contain the free radical scavenging molecule, melanin, and other molecules which are the targets of immune attack in melanoma skin cancer and vitiligo. More […]

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Conditions: Autoimmune disease, Autoimmune thyroiditis, Hypopigmentation, Melanoma, Vitiligo

Supplements: Boswellia (Boswellia serrata), Chasteberry (Vitex agnus castus), Phenylalanine, Tyrosine

Miscellaneous: 5-lipoxygenase inhibitors, Dopamine agonists, Melanin, Melanocytes, Proton pump inhibitors

Biomarkers in Autoimmune Diseases..

Posted on December 20, 2008 by Dr. Gary Pack

Autoimmune diseases can result from hormonal, immune and metabolic processes. This study was done to determine levels of prolactin (PRL), ferritin, vitamin D and tumor marker tissue polypeptide antigen (TPA) in autoimmune diseases, such as systemic lupus erythematosus (SLE), systemic sclerosis (SSC), rheumatoid arthritis (RA), polymyositis (PM), dermatomyositis (DM), multiple sclerosis (MS), antiphospholipid syndrome and […]

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