Carbonic Anhydrase in Ankylosing Spondylitis.

Posted on May 8, 2011 by Dr. Gary Pack

Ankylosing spondylitis (AS) is a disease with increased bone resorption and formation in areas of chronic inflammation. There is mainly involvement of the sacroiliac joints and of the spine. This present study was done to identify the proteins involved in the synovial membranes of patients with AS, rheumatoid arthritis (RA,) and osteoarthritis (OA,) to compare […]

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Conditions: Ankylosing spondylitis, Chronic inflammatory disease, Osteoarthritis, Rheumatoid arthritis

Supplements: Bicarbonate, Calcium carbonate, Catechins, Curcumin, EDTA, Resveratrol, Silymarin

Miscellaneous: Carbonic anhydrase

Thyroid Cancer Review.

Posted on May 8, 2011 by Dr. Gary Pack

Patrick, in Summary #375 writes that thyroid disease, including cancer and autoimmune disease, is rapidly increasing. PCBs (polychlorinated biphenyl) environmental pollutants are associated with thyroid cancer. They are still in fish, even in salmon from Alaska. Patrick, in Summary #387 writes that low iodine increases cancer of the thyroid. Low iodine increases the uptake of […]

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Conditions: Angiogenesis, Autoimmune thyroiditis, Cancer, Multiple sclerosis, Thyroid cancer, Thyroid disease

Supplements: Bifidobacterium sp., DIM (diindolylmethane), Glutathione peroxidase, Glycine, Iodine, Lactobacillus species, Milk thistle (Silybum marianum), Resveratrol, Selenium, Silymarin, Zinc

Foods: Brazil nuts, Broccoli, Garlic, Leeks, Matcha green tea, Onions

Miscellaneous: Element, Histone deacetylation, Japanese diet, Natural killer (NK) cells, Prolactin, Thyroid gland

Carbonic Anhydrase Inhibitors in Natural Food Compounds.

Posted on April 25, 2011 by Dr. Gary Pack

Carbonic anhydrase (CA) is an enzyme which converts carbon dioxide (CO2) to bicarbonate and a proton (hydrogen ion.) This is necessary to many physiologic processes, such as acid-base balance, breathing, and tumor development. A number of CA forms are targets for inhibition in treatment of cancer, edema, glaucoma, obesity, epilepsy, and osteoporosis. Resveratrol, catechin, silymarin, […]

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Conditions: Acid-base balance, Cancer, Edema, Epilepsy, Glaucoma, Obesity, Osteoporosis

Supplements: Curcumin, EGCG (epigallocatechin gallate), Milk thistle (Silybum marianum), Resveratrol, Silymarin

Foods: Red wine, Tea

Miscellaneous: Carbonic anhydrase, Hydrogen, Polyphenols, Sulfonamide

Liver Protection Activity of Virgin Coconut Oil.

Posted on March 27, 2011 by Dr. Gary Pack

Coconut oil (CO) has been known for centuries to have health benefits and is now seen as a functional food. Virgin CO (VCO) is antioxidant, antimicrobial, antiviral, antihypercholesterol and antithrombotic. Cold processing of VCO conserves the chemicals of coconuts, tocopherols, sterols, and squalene. It is 48-50% saturated medium chain fatty acid (lauric oil) and short […]

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Phytosome Complexes of Silymarin, Curcumin, Etc.

Posted on August 9, 2010 by Dr. Gary Pack

One class of very useful plant medicines is made up of polyphenols, mostly flavonoids. Polyphenols absorb poorly into water or lipids. The phytosome forms of polyphenols have improved oral absorption and are safe. They are used as anti-inflammatories, anti-neoplastics, for detoxification and for weight loss.Polyphenols bind strongly to phospholipids, even in intact plant tissue. Phosphatidylcholine […]

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Silymarin Treatment of Viral Hepatitis.

Posted on November 25, 2008 by Dr. Gary Pack

Silymarin is a component of the herb milk thistle (Silybum marianum). Silymarin is 70% of standardized milk thistle and most of silymarin is a flavonolignan called silibin. (Silibin is also known as silibinin.) Milk thistle is used to treat viral hepatitis, yet it is uncertain whether it is beneficial. This article is a review of […]

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Conditions: Alcoholic cirrhosis, Hepatitis, Hepatitis A, Hepatitis B, Hepatitis C, Liver disease, Liver toxicity, Prostate cancer, Skin cancer, Viral hepatitis

Supplements: Agrimony (Agrimonia eupatoria), Glutathione, Milk thistle (Silybum marianum), Phosphatidylcholine, Silybinin, Silymarin, Superoxide dismutase (SOD)

Miscellaneous: Flavonolignans

Milk Thistle Phytosome.

Posted on November 7, 2007 by Dr. Gary Pack

Milk thistle (Silybum marianum), an anti-oxidant, contains flavonoids that protect the liver. The liver detoxifies hormones and other chemicals produced in the body and is an easy target for damage by any toxins ingested. Silymarin is the active extract of Milk thistle which contains the following flavonoids: Silibin, silydianin and silychristin. Silibin is a flavonolignan. […]

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Conditions: Alcoholic hepatitis, Liver protection, Liver toxicity, Viral hepatitis

Supplements: Antioxidants, Bioflavonoids, Curcumin, Glutathione, Grape seed extract, Green tea, Lignans, Milk thistle (Silybum marianum), Phosphatidylcholine, Phytosomes, Silibinin, Silymarin

Foods: Soy

Miscellaneous: Phospholipids

Silymarin is Hepatoprotective in Cholestasis.

Posted on September 20, 2007 by Dr. Gary Pack

Silymarin (SIL) is an extract of Milk thistle (Silybum marianum), which has been used for 2000 years. Milk thistle has been used since the 16th century for liver disease and SIL has been marketed since 1969. SIL is a standard extract of the Milk thistle fruit and seed and standardized Milk thistle is 70% SIL. […]

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Silibinin and Hepatocellular Carcinoma.

Posted on March 6, 2007 by Dr. Gary Pack

Hepatocellular carcinoma (HCC) of the liver, which has no current effective treatment, is the world’s second most common recurrent cancer, with one million people dying of HCC annually worldwide. The treatment is poor at present because of drug resistance and the severe toxicity of the drugs used for chemotherapy. HCC cells are especially resistant to […]

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Conditions: Apoptosis, Bladder cancer, Breast cancer, Cancer, Chemotherapy, Colon cancer, Fungal infection, Hepatitis, Hepatitis B, Hepatitis C, Hepatocellular cancer, Lung cancer, Multidrug resistance (MDR), Prostate cancer, Skin cancer

Supplements: Milk thistle (Silybum marianum), Silibinin, Silymarin

Miscellaneous: Aflatoxin, Aspergillus mold, Liver

New Therapy for Age-Related Macular Degeneration.

Posted on January 25, 2007 by Dr. Gary Pack

Age-related macular degeneration (AMD) is a common cause of blindness in the elderly. New drugs are being tested to work against vascular endothelial growth factor (VEGF), a natural chemical in the body that causes neovascularization (the growth of new blood vessels) in the eye. Corticosteroids, which prevent the growth of new blood vessels, are used […]

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Conditions: Age-related macular degeneration, Angiogenesis, Blindness, Cancer, Neovascularization

Supplements: Beta-carotene, DIM (diindolylmethane), Fish oil, Glycine, Green tea extract, Lutein, Milk thistle (Silybum marianum), Selenium, Silymarin, Vitamin C (ascorbic acid), Vitamin E, Zeaxanthin, Zinc

Foods: Corn

Miscellaneous: Corticosteroids, Macula, Photodynamic therapy, VEGF (vascular endothelial growth factor)

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